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As particularly promising translational research avenues toward direly needed progress in the management of these disfiguring, deeply distressful cicatricial alopecia variants, we advocate to focus on the development of bulge IP and epithelial SC protectants such as, for example, topically effective, HF penetrating and immunoinhibitory preparations that contain tacrolimus, peroxisome proliferator activated receptor Оі, and or CB1 agonists tamoxifen 20 mg Localized solid tumors are often treated with surgery in their early stages

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